I mean what else can I say?

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Kuhl: Tyler and I are both from Michigan, and that’s where we met in college. When I still lived at home, I always watched TV with my family. Even when I moved to California, my mom still texts me about “Amazing Race” or “Survivor” and spoils things because she’s on the East Coast.

“Together the couple moved to Kopeopeo, a small 50 per cent Maori suburb in Whakatane where Chaplow, whose mother spoke Bengali and whose grandfather had been a missionary to India and wrote five books on Islam, was the traditional family doctor delivering about 130 babies a year, dealing with psychological problems, the lot.But it was his fluency in Maori, plus his affinity with Maori mental health that was most hard to come by, and highly prized, in 1970s New Zealand. “I was asked to join the Whakatane Psychiatric Unit one day a week,” he says “and it soon became clear that I needed to train in psychiatry if I was going to continue. So Becky and I and [by then] four kiddies upstumped and went to Brisbane.”That was a very dark chapter of my life,” he continues.

The bottom row of images shows cell proliferation in the suborbital area of the blind side eye30. The black arrowheads indicate the proliferating epidermal cells in the assay used to detect proliferation. Proliferating cells in the blind side of Japanese flounder injected with 9 cis RA and ATRA were less numerous than in control larvae at the pro metamorphic stage. The strong positive selection of genes involved in the RA system in Japanese flounder (aldh1l2 and rbp4b) and Chinese tongue sole (aldh1l1 and rdh12) (Supplementary Tables 17 and 18) and the enrichment of genes of the RA pathway in the DEGs during metamorphosis (rxra, rxrg, rarg, aldh1l2, rbp2, raet1, rdh12, rbp3, fake ray bans and lrat) (Supplementary Table 30) suggest their involvement in asymmetry formation. We hypothesized that DEGs of the RA signaling pathway might explain the acquisition of TH signaling pathway asymmetry during metamorphosis, and that this cross talk could be the basis for the generation of asymmetry in flatfish. Genes encoding isoforms of RA receptors (Rxra and Rxrb) that heterodimerize in yeast two hybrid assays (Supplementary Figs.